Treatment Recommendations for Major Depressive Disorder in Older Adults Major Depressive Disorder (MDD) in older adults presents unique challenges due to age-related physiological changes, comorbidities, and potential drug interactions. This paper examines evidence-based treatments for MDD in the geriatric population, including an FDA-approved drug, an off-label medication, and a nonpharmacological intervention. FDA-Approved Drug: Sertraline Sertraline, […]